Interesting question. YankeeJim and several other pretty good players say "don't hit with backspin" as it increases 'VEM deviation'. OK?
I spent 3 sleeves mapping my L79 Bladez and use backspin a lot. If you look at my stats you will see that my average distance to the pin in 18 yds (includes everything from when I started this game). I am averaging more like 9 yds now (using backspin) and when I miss, it's usually because I miss the 'Ding".
The point here, is that, if you have mapped your clubs and hit pretty close to the 'ding' your clubs will perform pretty predictably. The important point is KNOW what your clubs can and will do. There are a lot of holes where 'running the ball to the pin' (i.e. no backspin) is not a good option as things like bunkers to prevent that.
Also it is important to realize that the courses & club performance change (by the day??). I use Bilko. 2 days ago I applied a minus 5 correction to Bilko's numbers and was shooting 5-6 under on 9 holes. Today I am applying -1 to -2 to get the same result. Same clubs, same ball, same WGT., BUT new day!
BTB when I mapped the irons, I mapped them with no-spin, full 'top-spin' and full 'bottom-spin' - for full power, pitch, chip, flop and punch. (that's why it cost so many balls).