I hit the ding probably 50% on a bad day and 70% on a good day. Most of my clubs have a speed from 11 o'clock to 1 o'clock. I ding them equally well. My putter has a slow meter. I have trouble dinging it.
My meter varies from really smooth to a little clumpy, but doesn't fail. I use Chrome, pepper flash turned off, no extraneous processes running.
I don't line my mouse up with the ding line. Once I release the meter, I just concentrate on a point slightly in advance of the ding line and try to click when it gets there.
I don't hit off-ding on purpose for either wind or break. Hitting the ding does not appear to ruin my shot. I do hit way off ding for draws and fades, which I use rarely. It costs about 20 yards to do that, but is sometimes worth it, as opposed to hitting through a dogleg (or short).
I suspect the method will vary considerably, depending on the individual reflexes and so forth. I'm 72 and sometimes I'm less polished and more spastic than at other times. One scotch on a bad day may help. Three scotches never helps.