It's not just this hole, though there may be a more common issue on this hole (I haven't seen it). On any shot of any hole the ball can come off of the club in any random direction, even when the perfect line is hit. This is not a common occurrance, but I've seen it plenty. My co-worker has blasted it into the water on 17 of Kiawah at least twice when making flush contact with the ball and aiming well left of the hole. This seems to happen quite frequently on putts.
Another possibility is that if you are coming in at an odd angle sometimes the wind directions are *very* different from the zoomed in view and the zoomed out view. The problem is that the zoomed in view always comes from the same angle while your zoomed out actual shot view can be from different angles. I'm not sure how accurately the wind gage accounts for this. It would be very nice if the zoom in view was from the same angle as your shot, but I doubt that is technically feasible.
I also agree wholeheartedly about that stupid patch of "fairway" in front of the green on 13. You can land inches from the green and the ball will just plain stick. This leaves very little room for error on your approach.