Scott I have changed nothing in the nvidia control panel, all is running at default settings.
I run nvidia type cards, actually gigabyte. gtx1030, gtx570, and gtx1060. And the jagged and blurry is probably more associated with the AA settings on your card.
My resolution discussion goes back in time and current gaming. this 22 inch wide monitor is set to 1600x900 my other is set to 1920x1080, if I go in game and set game resolution to 800x600, one the game is actually now too large for the screen and it looks like crap. This would be in a windows mode. Even in full screen there is no detail. 800x600 is too pixelated and grainy appearing. It was even worse with a CRT. Granted it appears that the game pictures don't change per different resolutions, but the software that is layered onto the game does. For me anyway, and I believe others, that is why the game, from moving the aimer, to the speed of the meter, to the width of the lines, to the length of the meter all display differently with different game resolutions, even in a windowed mode environment.
Yes I could probably go into my GPU card settings and change things, but for just this game, it is not gonna happen.