What kind of weeds? 30-40? 50-60? 70-80?
You can sometimes hit forwards out of 30-40 and get a reasonable result....but for anything deeper than that, I find that a shot played sideways into the fairway is the best bet. Punch one of your wedges, but don't expect much distance. Basically, you're playing for par after finding the weeds.
And if anyone's figured out a better method than that? I'm all ears.....