f5 is one I use a lot on my laptop, but CTL+F5 is good if you want to clear cache and refresh at the same time. Hard to do on the laptop since I need to use the Function (FN) key to utilize the upper row "F" keys.
Avoid the alt+f4 and or ctrl+f5 or f5 if someone suggests it in a multi player game. LOL
If all windows are closed and you are at the desktop, alt+f4 will give you a menu to restart/shutdown. Typically shutdown is the first option and already selected.
Alt+F4 then enter is fun when a coworker is on their desktop with nothing open and ask me how to do something again for the umpteenth time LOL.