not really, it depends on the club. For example, the 20-30% rough almost doesn't affect wedges, but it really hurts the carry distance for long irons and woods (hybrids are great out of it though)
It affects the carry distance more than the total distance too, since there is less spin coming out of the rough.
Best thing to do is hit some test shots, and write down what your carry distance is out of each lie for each club.